Need help with linear regression

zyzy

I'm trying to run linear regression with over 300000 count in excel data (3500 in row, 90 in column). With most of the data around 80-99 is number. Tried running the process but took over a few hours, so i stopped trying.
Do i have to reduce my numbers or how can i run the process?

Also do i have a way to change polynominal to numerical or something that could have me run linear regression. I have polynominal columns for my label and id.