Can Analysis without change Offset

Hi

Suppose, for side crush of a car, after performing the analysis(Create mesh, define MAT, Prop, Contact ,.....  I will Decide to change the thickness of some sheet's, so , I should define offset for Sheet's that have a change in thickness and then i should change some parameter's such as Contact, Spot weld , ....

Therefor, in analyzing a car that includes many hundreds of mesh, These changes will be very time consuming and costly.

Is there a good solution in this regard?