When a user tries to run the HyperMesh script from SimLab, the 'ALTAIR_HOME' env will be changed and it will conflict with the HyperMesh installation path.
The conflict can be avoided using the below methods.
1. Using the following Python code 
CODE:
#import subprocess module is used for accessing the system commands  import subprocess ,os  #To avoid the conflict between the SimLab and HyperMesh installation path store the ‘ALTAIR_HOME’ env in a python variable and clear the env.  Altair_Home = os.environ["ALTAIR_HOME"]  os.environ["ALTAIR_HOME"]=''  #Store the tcl script path and HyperMesh installation path in a python variable.  TCLScript = "./HM_Script.tcl"  hmBatchLoc = "./../hwdesktop/hm/bin/win64/hmbatch.exe"  #To start HyperMesh and execute the tcl script in batch mode use the below codes  Arg= hmBatchLoc+ " -tcl " + TCLScript  subprocess.call(Arg)  #After executing the tcl script restore back the ‘ALTAIR_HOME’ env  os.environ["ALTAIR_HOME"] = Altair_Home
 
SAMPLE SCRIPT:
import subprocess,os  Altair_Home = os.environ["ALTAIR_HOME"]  os.environ["ALTAIR_HOME"]=''  TCLScript = ""C:/Users/Documents/HyperMesh_Scripts/HM_Script.tcl"  hmBatchLoc = "C:/Program Files/Altair/HM_2021.2/hwdesktop/hm/bin/win64/hmbatch.exe"  Arg= hmBatchLoc+ " -tcl " + TCLScript  subprocess.call(Arg)  os.environ["ALTAIR_HOME"] = Altair_Home
  
2. Using the following batch script 
Use 'setlocal' and 'endlocal' batch commands as below to avoid this conflict.
 
BATCH SCRIPT: 
REM To get the script file to be executed in SimLab
set script_name=D:\\Script\\simlab.py
REM To get the SimLab.bat location
set simlab_bat=D:\\Altair\\SimLab_2022.1\\SimLab.bat
REM To get the ALTAIR_HOME path and launch HyperMesh
set ALTAIR_HOME=D:\\Altair\\Hw_2021
set hmbatch=%ALTAIR_HOME%\\hwdesktop\\hm\\bin\\win64\\hmbatch.exe
REM To localize the changes made to the variable 'ALTAIR_HOME'
setlocal
REM Launching SimLab.bat and executing the python script.
call %simlab_bat% -auto %script_name% -nographics 
REM To revert back the changes made to the variable.
endlocal
REM Launching HyperMesh and executing the tcl script.
start %hmbatch% -nocommand -h -tcl %script_path%\HM_Script.tcl