By using the connection between SimLab and CATIA we can generate a parametric model. This way we can automate the simulation process in SimLab, which we can use to create an optimization in HyperStudy. This particular model is a Heat Sink, where we want to maximize the heat dissipation and minimize the mass.
In the document, you'll find all related to the connection, how to automate with tips and tricks, as well as how to setup your model for optimization in HyperStudy. This is a document with more complicated model related to these videos:
https://www.youtube.com/watch?v=sPZW9RC_GL0
https://www.youtube.com/watch?v=HagwgDUY68s

For more reference of the Sobol sequence:
https://community.altair.com/community?id=community_blog&sys_id=84e6913fdbd22910cfd5f6a4e29619a0&view_source=searchResult