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Hi,
Kindly confirm whether you are using student edition or full version.
And, kindly delete the settings files as mentioned below and try opening HyperMesh and let us know if the issue still persists.
https://community.altair.com/community?id=community_question&sys_id=044688761b2bd0908017dc61ec4bcb69&view_source=searchResult
If this's the 1st run of Hypermesh, I think you have some issue with downloaded files. Download them again and don't forget to check MD5SUM before installing.